Brain Kidney Interactions in Post Traumatic Brain Death

Ahmed Youssef Kada; Mourad Kastali; Kheireddine Abdelouahed Bouyoucef; Kouider Sahraoui

Brain Kidney Interactions in Post Traumatic Brain Death | AB Journals

Brain Kidney Interactions in Post Traumatic Brain Death

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African Journal of Biology and Medical Research

Vol. 3Issue 12020pp. 9–14Published 4 March 2020

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Abstract:

Brain death is the cause of a major inflammatory systemic response syndrome (SIRS) affecting all the organs and partly responsible for their dysfunction. One of these consequences is kidney failure (AKI: Acute Kidney Injury). Between September 2008 and September 2013, renal function was analyzed in patients admitted for severe head injury who progressed to brain death. Impairment of renal function has been demonstrated in these subjects upon admission, suggesting a direct interaction between the brain and the kidney. An early deterioration of renal function in the subject in a brain death state is often highlighted in our study, its occurrence results from the addition of hemodynamic, neurohormonal and inflammatory factors.

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