Gas Chromatography-Mass Spectroscopy and Fourier Transform Infrared Spectroscopy Profiling of the bioactive compounds present in the methanol extract of Solanum aethiopicum from Imo State, Nigeria

Abstract:

The study aimed to access the bioactive compounds and functional groups present in Solanum aethiopicum using the Gas Chromatography coupled with mass spectrometer (GCMS) and Fourier Transform Infrared Spectroscopy (FTIR). The GCMS showed Solanum aethiopicum showed a total of thirty-seven bioactive compound with the highest abundance being Squalene (21.13%), Palmitoleic acid (16.63%), 13-Octadecenal (16.63%) and 9-Octadecenoic acid (17.62%). Fourier Transform Infrared Spectroscopy of Solanum aethiopicum showed the presence of functional groups which include alkanes, alkenes, alkynes, primary (10) and secondary (20) amines, amides, imino, epoxy, peroxides, carboxylic esters, ethers, primary (10), secondary (20) and Tertiary (30) alcohols, phenols, aldehydes, thiols, cyanate, isoyanates and alkylhalides. These bioactive compounds with reference to literature revealed a variety of biological functions spanning across antibacterial, anti-inflammatory, anti-oxidant, analgesic, antimalarial, antifungal, anti-tumour, neuroprotective, anti-tumour, anti-cancer, anti-seizure, anti-allergy, anti beta-amyloid protein aggregation.