Prevalence and Antibiotic Susceptibility Profile of Isolated Blse-Producing Klebsiella SPP in Urinary Tract Infections at FANN National University Hospital (Dakar/Senegal).

Publication Date: 12/07/2024

DOI: 10.52589/AJBMR-ZHACEWRG

Author(s): Niokhor Ngobe Sene, Aissatou Ahmet Niang, Madiagne Der, Fatoumata Diallo, Aissatou Gaye, Youssoupha Fall, Sény Ndiaye, Mouhamadou Lamine Dia.

Volume/Issue: Volume 7 , Issue 3 (2024)



Abstract:

This is a retrospective study covering the period 2022-2023 on urine samples received at the bacteriology-virology laboratory of the CHNU of FANN. The aim was to determine the prevalence and sensitivity profile of ESBL-producing strains of Klebsiella spp to other antibiotic molecules. A total of 549 urine samples were positive for a bacterium, of which 113 (20.58%) were attributable to Klebsiella spp., with a predominance of Klebsiella pneumoniae n=90 (79.65%). 59.26% were producers of extended-spectrum betalactamase (ESBL), of which 56.25% (n=27/48) were of hospital origin. Good sensitivity was noted to imipenem (78.40%) and amikacin (70.59%).


Keywords:

ESBL, Klebsiella spp, Urinary tract, Antibiotics.


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